Includes a full line-by-line review of your results in a 45-minute consult for current wellness clients or as an add-on to your New Client 90-minute Integrative Health Assessment.

• Copper, RBC and Plasma

Evaluate copper stores and accumulation

• Iodine, Serum or Plasma

Monitor exposure to iodine; evaluate for iodine deficiency, excessive iodine intake, or iodine in the workplace/environment.

• Methylmalonic Acid (MMA), Serum or Plasma

Serum methylmalonic acid (MMA) measurement is used to evaluate individuals with signs and symptoms associated with vitamin B12 deficiency or congenital methylmalonic academia.

• Paratthyroid Horrmone (PTH) Plus Calcium

Differential diagnosis of hypercalcemia. PTH is an 84-amino acid peptide hormone that is responsible for the regulation of serum calcium levels within a narrow range.

PTH is secreted in response to decrease in serum calcium levels by increasing the renal reabsorption of calcium and lowering reabsorption of phosphorus. The measurement of PTH is a useful tool in the differential diagnosis and management of hypercalcemia. PTH assays can be of help in the diagnosis of tumors and hyperplasia of the parathyroid gland, as well as in localizing hyperfunctioning parathyroid tissue by assay of samples obtained via venous catheterization. The native or intact (1-84) PTH has a short half-life, measured in minutes, whereas the carboxy and midmolecule fragments, which are biologically inactive, have half-lives 10- to 20-fold higher. The high concentrations of biologically inactive fragments have interfered with use of C-terminal or midmolecule assays for evaluation of parathyroid function in patients with impaired renal function. Intact PTH assays provide a more accurate assessment of parathyroid patients including those with various renal diseases.

• Vitamin A (Retinol)

Differential diagnosis of hypervitaminosis A. A combination of a low serum carotene level and a low vitamin A suggests inadequate vitamin A nutrition.

Vitamin A is the name given to a group of biologically active, fat-soluble molecules that includes retinol, retinal and retinoic acid. These retinoid compounds are derived from the plant precursor molecule, β-carotene. β-carotene (also referred to as provitamin A) has a structure that consists of two molecules of retinal linked at their aldehyde ends.1 β-carotene is converted to vitamin A by intestinal absorptive cells and hepatocytes. Vitamin A is stored in the liver and transported to extrahepatic tissues bound to retinol binding protein and albumin. Both retinol and β-carotene levels are measured in plasma for assessing vitamin A inadequacy and/or toxicity.

Vitamin A exists in humans in several forms and is tightly controlled. Naturally occuring forms of vitamin A include retinol, retinol esters, retinal and retinoic acid. The alcohol form, retinol, predominates in the circulation, but it is too toxic for storage. Instead, the liver stores as retinyl esters - principally palmitate. The active form of vitamin A in the visual cycle is the aldehyde form, retinal. Retinoic acid is the form in tissues responsible for the biological actions of vitamin A in cellular division and differentiation.

The most important measure and for the estimation of vitamin A status is circulating vitamin A as retinol. Serum retinol levels do not accurately reflect liver retinyl ester levels. Despite this limitation, serum retinol is still useful because the levels will diminish once the supply from the liver is diminished. The serum retinol level at which vitamin A deficiency occurs will coincide with the manifestation of night blindness, due to the interruption of the visual cycle by lack of retinal. Other more serious symptoms will occur later when retinoic acid is depleted by even less available hepatic retinyl esters.

The body must acquire vitamin A from the diet in order to sustain a number of essential physiological processes. These include vision, organogenesis, tissue differentiation, immune function, reproduction, embryonic development and maintenance of healthy skin and barrier functions. More than five hundred genes are thought to be regulated by vitamin A.

Vitamin A deficiency only manifests when liver stores are depleted by prolonged reduction of dietary intake. In healthy individuals, serum retinol concentrations are homeostatically controlled and do not begin to decline until liver reserves of vitamin A are dangerously low.

Excessive levels of vitamin A can lead to toxicity. Vitamin A intoxication is a concern in normal adults who ingest more than 15 mg per day and children who ingest more than 6 mg per day of vitamin A for a period of several months.

• Vitamin D, 1, 25-Dihydroxy (Calcitriol)

Aid in the diagnosis of primary hyperparathyroidism, hypoparathyroidism, pseudohypoparathyroidism, renal osteodystrophy, and vitamin D-resistant rickets.

The 25-(OH) vitamin D form of the hormone is the principle circulating reservoir in plasma and is generally the best indicator of overall vitamin D status.

Humans get vitamin D from their normal diet, dietary supplements and from exposure to sunlight.1-5 Ultraviolet B irradiation of the skin drives the conversion of 7-dehydrocholesterol to previtamin D3, which is then rapidly converted to vitamin D3.1 Vitamin D from the skin and diet is further metabolized in the liver to 25-(OH) vitamin D (or calcidiol).1-5 Calcidiol is the principle circulating reservoir of vitamin D in plasma and is generally the best indicator of overall vitamin D status.

Your requisition form will be emailed to you within 48 hours of purchase. When you receive this requisition form, print it out and take it into any LabCorp* in the area. You can find your nearest LabCorp on their website. Appointments are not required. You will have your blood drawn and a urinalysis done there. Please note: you need to be fasting at least 8 hours before, so it's best to go before you've eaten breakfast in the morning. Your results will be sent to our office about 24 to 48 hours after you've had your blood drawn and we will email them to you.

*LabCorp is an American company. We also do not have the ability to order for New Jersey, New York, or Rhode Island.

** For Canada, please contact us for instructions to order your lab work. Additional fees apply.